系統生物醫學系主任 教授
職稱：教授
學科專業：系統生物醫學
研究方向：多組學、人工智能、生物醫學大數據、衰老
行政職務：系統生物醫學系主任
電子郵箱：luojh@jnu.edu.cn
個人介紹：羅鈞洪，醫學科學博士，太阳集团app首页教授、博士生導師。國家引進海外高層次人才計劃青年人才（第十六批），國家自然科學基金外國優秀青年學者，廣東省珠江人才計劃引進高層次人才，回國前曾在澳大利亞聯邦科學與工業研究組織任研究員（終身制）。主要研究方向為基因組學、三維基因組學和生物信息學，長期從事生物醫學大數據相關研究，專注于人工智能技術在單細胞測序、T細胞受體組庫和其它生物醫學多組學大數據分析中的開發和應用。在Cell、Nature、Nat Aging、Nat Genetics、Nat Protocols和STTT等頂級期刊發表30餘篇學術論文，總他引超過20000次，獲授權美國專利1項，國家發明專利3項。
2007.8–2011.6，澳大利亞國立大學，醫學科學，博士
2002.7–2006.6，澳大利亞新南威爾士大學，生物信息學，工程學士（Hounors degree）
2019.6-至今，太阳集团app首页，太阳集团1088vip，教授
2016.8-2019.5，澳大利亞聯邦科學與工業研究組織，Health & Biosecurity，研究員（Tenured)
2016.3-2016.7，美國傑克遜實驗室基因組醫學研究所，Genome Sciences，助理研究員
2012.9-2016.3，美國傑克遜實驗室基因組醫學研究所，Genome Sciences，博士後，合作導師：阮一駿
2011.7-2012.9，新加坡基因組研究所(GIS)，Genome Technology and Biology，博士後，合作導師：阮一駿
2006.7-2007.7，澳大利亞悉尼大學，獸醫學院，生物信息科研員
1.Chao Ke*; Boya Huang*; Jian Xiang*; Jinlian Liang*; Guangjie Wu; Minghui Qiu; Kai Cheng; Lipeng Mao; Wen Lei; Yang Hu; Xiaogen Tang; Yizhen Tian; Guobing Chen#; Oscar Junhong Luo#; Hongyi Zhang#; Secreted Clusterin Inhibits Tumorigenesis by Modulating Tumor Cell and Macrophage in Human Meningioma, Neuro-Oncology, 2024, 26(noae034)
2.Bei Zhang, Zhiyao Ren, Jianfu Zhao, Yue Zhu, Boya Huang, Chanchan Xiao, Yan Zhang, Jieping Deng, Lipeng Mao, Lei Tang, Dan Lan, Lijuan Gao, Hongyi Zhang#, Guobing Chen#, Oscar Junhong Luo#. (2023). Global analysis of HLA-A2 restricted MAGE-A3 tumor antigen epitopes and corresponding TCRs in non-small cell lung cancer. Theranostics, 13(13):4449-4468.
3.Zhenghu Jia, Zhiyao Ren, Dongmei Ye, Jiawei Li, ……Guobing Chen, Peiling Li, Juan Ouyang, Peisong Chen#, Oscar Junhong Luo#, Yifang Gao# & Zhinan Yin# (2023) Immune-Ageing Evaluation of Peripheral T and NK Lymphocyte Subsets in Chinese Healthy Adults. Phenomics, 2023 May 23.
4.Xiao, C., Ren, Z., Zhang, B., Mao, L., Zhu, G., Gao, L., Su, J., Ye, J., Long, Z., Zhu, Y., Chen, P., Su, X., Zhou, T., Huang, Y., Chen, X., Xie, C., … Zhang, H., Wang, P.#, Liang, X.#, Luo, O.J.#, Chen, G.#. (2023). Insufficient epitope-specific T cell clones are responsible for impaired cellular immunity to inactivated SARS-CoV-2 vaccine in older adults. Nature Aging, 3(3)
5.Lai, W., Wang, X., Liu, L., Xu, L., Mao, L., Tan, J., Zha, X., Zhan, H., Lei, W., Lan, Y., Chen, G., Li, Y.#, & Luo, O. J.# (2022). Single-cell profiling of T cells uncovers a tissue-resident memory-like T-cell subset associated with bidirectional prognosis for B-cell acute lymphoblastic leukemia. Frontiers in Immunology, 13, 7258.
6.Luo, O. J*#., Lei, W.*, Zhu, G.*, Ren, Z.*, Xu, Y., Xiao, C., Zhang, H., Cai, J., Luo, Z., Gao, L., Su, J., Tang, L., Guo, W., Su, H., Zhang, Z. J., Fang, E. F., Ruan, Y., Leng, S. X., Ju, Z., … Chen, G. (2022). Multidimensional single-cell analysis of human peripheral blood reveals characteristic features of the immune system landscape in aging and frailty. Nature Aging, 2(4), 348–364.
7.Hu, Y., Xu, Y., Mao, L., Lei, W., Xiang, J., Gao, L., Jiang, J., Huang, L., Luo, O. J.#, Duan, J.#, & Chen, G#. (2022). Gene Expression Analysis Reveals Age and Ethnicity Signatures Between Young and Old Adults in Human PBMC. Frontiers in Aging, 2, 77.
8.Di, B.*, Jia, H.*, Luo, O. J.*, Lin, F.*, Li, K., Zhang, Y., Wang, H., Liang, H., Fan, J., & Yang, Z. (2020). Identification and validation of predictive factors for progression to severe COVID-19 pneumonia by proteomics. Signal Transduction and Targeted Therapy 2020 5:1, 5(1), 1–4.
9.Li, X.*, Luo, O. J.*, Wang, P., Zheng, M., Wang, D., Piecuch, E., Zhu, J. J., Tian, S. Z., Tang, Z., Li, G., & Ruan, Y. (2017). Long-read ChIA-PET for base-pair-resolution mapping of haplotype-specific chromatin interactions. Nature Protocols, 12(5), 899–915.
10.Tang, Z.*, Luo, O. J.*, Li, X.*, Zheng, M., Zhu, J. J., Szalaj, P., Trzaskoma, P., Magalska, A., Wlodarczyk, J., Ruszczycki, B., Michalski, P., Piecuch, E., Wang, P., Wang, D., Tian, S. Z., Penrad-Mobayed, M., Sachs, L. M., Ruan, X., Wei, C. L., … Ruan, Y. (2015). CTCF-Mediated Human 3D Genome Architecture Reveals Chromatin Topology for Transcription. Cell, 163(7), 1611–1627.
*共一作者 #共通訊作者
The Jackson Laboratory Community Award，The Jackson Laboratory，2015
CSIRO Julius Award, 澳大利亞聯邦科學與工業研究組織，2018
太阳集团1088vip科研工作先進個人，2020、2023
太阳集团app首页第九屆學術委員會委員
廣東省醫學會醫學人工智能分會第一屆委員會委員
廣東省醫學會老年醫學分會第九屆委員會老年免疫學組成員
廣東省精準醫學應用學會單細胞科技分會會員
